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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7ee1df45bc799a2aa47260e87c2a3216bd78d4b70393c9c6f9fcd04ae9a9b45' 
  AND token = 'uOmA6kxPZeNZKFBETgWceEde2Bq3aeBXSrXlqOdqk4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}