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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28252c2e21a0a5643e3b6ad21fb787d0105b2aa262b50e18c052711bf3203b7e' 
  AND token = 'G9BWDHjUEdbW/CunglqG2i58wTgzcKqZs9YBdDdhUxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}