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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9adf4b9a4d574ed44f33a4226ef509a75020864089b97b7a9b1990fc0be7a3cc' 
  AND token = 'Y3XfuYjuPhpGfPNQSfGbysWcwJNvE1Tg5HU2OvYr6hM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}