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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1305561e1cf3bf1e74f5379252f4abfbaae3b5a6ddbd89fbcff7f271c6631445' 
  AND token = 'yciEXwzwhM+u1ONNrAd1LMo6ew/yApLq86eUidAIyYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}