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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e006ed0c5fac5b74ce0fb1ef1cc7fe1f978dba9c0736449f8559db608208f6d' 
  AND token = 'H0CujTcE57tbipXxV78y1JHao6AUNeBIrZ1ZXh7n0Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}