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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f24d015cc488f82cafade9d7f07a4c636f3381f355b2a1bb31b1d3cfb78a554a' 
  AND token = 'KMCCHV+kn913/7zHtXiX0KH6mO+BEI93c33ZWQzb93I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}