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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fd12d6f74f6f4f675abfa08d5b706dae79bb972a81eb36f0097e4e0704f7eb1' 
  AND token = '5O6xIWQS2hNar8Cjyp3nMnpvUozPQSeAIQ2dFo7lc6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}