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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4568f22d257be2e58c9b26b34d0019aa3378b5cb4aa9d8502175e8f5dcedc7e8' 
  AND token = 'Hr8a1qVsyUZn0NfMETC8gs5/Ws5oMj5V5E4Sibouv4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}