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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46bdd51870e1879ec3cd1394b9b78e4b0e079558a9910bc923e79ba2c0b5a1e5' 
  AND token = 'ye00xyFLTPfLpjjGqCorg4kPqr6LrM/4afUh2bMbbu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}