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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0466a5bfa67fb6ca3e68b3cb1dc61ec0e3c17d61a47a90b64876ed7a4fca08c' 
  AND token = 'VDN24XFXSxJOfPPdKXKzQTzwNu2HWA614+7xOzNKIO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}