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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd362e6f76160b37702ebe33afae9cc5482649f922b07722ca7f302a2bfb4145' 
  AND token = 'cFeYyTXAb1XQiDxLL6DvcSRmeyB2lmTUToYHK+mvjjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}