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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b377cb849e81cec937edb11da9bab72f43abb37831feca7593e1f913ce3b4e88' 
  AND token = '2qLZLg4Y6vD1zG29LcA0vPVox8PnzGzaNCnQHFtxHz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}