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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '053f42e141525e37f87b3adc30ba211d3efe25f1528e9848441bb2dbf2a37d01' 
  AND token = '0dy0XyOEIiSz7mVZNTVfs8GvjZOsrXzUyBgvZVUEHkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}