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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74a6cbc03b4e15e12bded54beab352acb0bdbaf71cc6617f6a622024cfb7db5f' 
  AND token = '+Dz8nwIdK5XCWTTK5acSZqF+kKRu6XT4HKB77RCEsh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}