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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e3e277c18b1773d90b3537d5052eea57ba037db9074c6d83140f65c39b2c850' 
  AND token = 'HeR4ucp/upMxC/MioVXsqGhgtLmod94j5eY2FH2+X/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}