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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da841ae9ed14bb15d18854f4b757b0fc033c3938e1e8e500691350beae4753cb' 
  AND token = 'PgXwHmOpWbB5uE7mwpDR2xIXKEoXYpirxwoP1Ta0Y6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}