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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51f1ef6fe9bbc06751d767c84f0e5ba2017111bb3e03c176b4e25c5a05b6fac5' 
  AND token = 'AHdW2ASgz0ATp9702B6emqfe3cmRRAwEvVFbL8hhcGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}