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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7625916ff2a615f69ffd1140c1648cfd26fe14080bf01103f6c5cbc2ca13944' 
  AND token = 'gZEzEeuxoJ0ZSyrEF5q2UyIeZiS6kb4JWRNBKUC6sMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}