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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72fe282d677fcf3a72f9946b5da7f18d635f681b0af0f0527e5f0b1e732dcb21' 
  AND token = 'bvSl5I3Yxd8Ftk3BwnQdE6sh6bgvuJY2KRVBjoI2pCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}