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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1797ed0f01c35f920dc4e65e8a2488ddb9050394acfa8113002e6a266dbaf029' 
  AND token = 'AYJfpVB6AvpOT2bKoWVGB8HmHvxC2rmdSGJ0MRL1Qjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}