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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8965e3c527051ed782afbe8ccdffd6a5d06cdd34daf7d7987577057ed8453ca5' 
  AND token = 'Tbclt/GjAYnZZF+1tnaTTVWdVDRKrEm7MXlp4sAWvXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}