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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af4a313be1623465605ddd5705b9ec7e343e6c154b94f746605d8abfe8a343b2' 
  AND token = '4ztpuOX3bBalicaZalXrF47H9IU6vysbsPE/njoSYWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}