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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1da03ea09ff4180821d85ce1754ac1c2ae7bd291126b38fb2971c434d4510db' 
  AND token = 'wN4DEiFBAJ8zez1dHF0IVXcxzGMnc0QjCtQT+EquOpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}