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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4f75b3b94c84fb1c09934265e6c78b3224202c4ff7eb9084b5a6c04dd26882c' 
  AND token = 'Nwg7Ch3vj3Z5pQ2/Eo4/etkhnhgZ807dtNPEkX1Gidg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}