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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a36d97f02db47e03f2bd9b455909f1ee27cef1786a4be10bdf07461fda060b6' 
  AND token = 'ce0MOB5V5zz388OTotan7WWxPsBFoCOB7wDeULM9Bj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}