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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c144bf15e779f74d0dffe5aca6f4a94cf3c60c2caba124e8219de91530824363' 
  AND token = '2P0OgTWx/RCtiYWvPr9E55iO3+w+XIM5ucftAR4b1dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}