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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd88d4d224342bf022eded44575394c6c6ec2cada9b4d2ed376dd365dd69a093' 
  AND token = '/UxCBgbSEguBc5ZF91vtYIXz10V2bli1ntE2X4htGsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}