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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05561a85cad5c94c7ede9a5634a2f5265305705c9a1d6d359f658c38afa19e5f' 
  AND token = '8cnTpUoVTTR0CDGahevur086j3ZXekRzRcZYZxId1U0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}