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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15ebdb6fe7e039f8f83d61babacd70d0e2462e8cbd361f46e95d7459803ba95a' 
  AND token = 'qWNeAgPFt7xk1IOzhu+VZECHhyZ4o61L0Dgvh1yDHXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}