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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dcbd0c21bf7a841e41995e1aeb3f601261f97899dd889255e85485125c9340e' 
  AND token = 'YqPHfVbBa+A3aGcAnAmlE8WBWyZK+QX55fV2NetTI1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}