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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5006edb3e10f3f6172c690313b9e1860a90d9a3eff33492e9c695e0e2666bf6c' 
  AND token = 'e+iuHjgaYHuZa2dL/a27y9n2KZdqiQP9sBAM0U6GJv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}