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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5469abfbe96faf196c5a455d3838abc5a878303e51978f203a0379ce7e876960' 
  AND token = '8CBtxni33Sj5Qayyh6PR8ftsxF7FiIrPTLK3XL8d6tU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}