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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb62c9b3f46b8f8213f575a413674760f0be3af91a3dcd8e3547f110bac51c05' 
  AND token = '6yKL57Yw2aOn4iROIYQp1fZUzYn6Qc0XhKCqu5RLfHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}