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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bf5ba870c772b7f4662e58f2004287199f2e218651fa7b86e29cbf30bfdaf2f' 
  AND token = 'WIuaWxeKHy+YmW/t8QM1b9COtFAlPbrN1hYUs8/pLuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}