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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0e5e9915602a0a664020e50a36ad7e760cb438a2eef42e007b9d155f72f3c59' 
  AND token = 'ThO/w2gGFzUMFIhxLBZf/I1VL7ee1cTHKEFAKdmF8S0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}