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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '751ff1ff56b91b4390405afa3a74dba4754016d69620259559e4c6e618fac458' 
  AND token = 'xX3SX1trwL6h5VHM3F2BhZZM7HcmP88uBfNfqUXpDI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}