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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f335f5060aa12fdd7686a21418fd36107df38eeab2e3ecf02a6575f765df1c43' 
  AND token = 'BjpXSJWzcAdzDpWJ6oxwJrDr8DR9/uvfsaN4AqFcyys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}