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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ee8170d8f9d44ed8b9413c5a76b21633ff8560317839518344264568468d29' 
  AND token = 'kD2cHVFX4a0Qg3XHD2z1QtArD9rDDCbADTDJo+brd24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}