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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '752736aaa34c836b511b34cdf8c7a7f6b3151e84efce0e90727a7eacc478b7d7' 
  AND token = '7S3k9Nx/35/DwMSg0l0/BDo8KiyqBZ+0FcVe/m+/a8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}