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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49209d950da401ffffae6584d4c506e1927c53caa1e5638f57851f4d2ca17dac' 
  AND token = '5IQ6NmlBwn1ZZLNggjsxl+hdPFYNEKk313mpsd7H38k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}