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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27878429a124afc8c30393132ec41c0edbdc1055447f04fc20697fa7c02efe94' 
  AND token = 'fB6XM7XLPBqUoh3L2OAW7NfkCVSTo7qXtbrBc+EXTHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}