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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd303d15048eb7dc03d13ddcd67962afde233e8153b5f460b56951c3148b66c02' 
  AND token = 'CTFG228uVX6Fl+9Y4nPB7rc5VlEVFUNW//s4QWrjkEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}