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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dfc7df28ba6a239ed4fc31440b55c9797cc9ad9f47913bddeffc85c82a4f3fe' 
  AND token = '80bmgUT3BP4Sm4zxaIPaA2rkqIT9/NhhuzjjIgdRMZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}