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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79e4fbbe30ec2b8c3ee1c34c14784389c75a3cb456193c0c8b48edceee52427f' 
  AND token = '4mef08DGa9KHJosoqKlCgZsyYd9QVMTqj64dPQcYCro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}