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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46bd5f55bd76eb1692aae4c0ba2f9246cdfbb8f20fef10c4add7df8dc4619c79' 
  AND token = 'VHVeDDTtUMVMX2h7RSMjj9zwaT03+AvU6sM8fkCkhZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}