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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f25b2d801a6490af1e4ee70efd59c00ee1d12cc04639a2fd7d5dbb1faa79e8e9' 
  AND token = 'W2Tzng3XjKWT2jKvdTopplxktA7VBEtS2jLqfC8d5rc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}