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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5a54c77271eb277e3264278567222a93c318e53d86245fac43dee4c1dbce86b' 
  AND token = 'IYqwMt0iyMzK5UaYMPQmRgR/XeG2sVL8SoxkqH7Mkic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}