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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84b04f6a744045659838a3f49159ec321caa21d4a4bbc9e0ba3b0e74edc9993e' 
  AND token = 'ANV8QhrRiq3X/b0tYAONrf+OKm2U9H73egCzmFXkGB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}