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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79b9c6aba6bc4d0cde33e9d769bbe97aa95f53794e0763ea96f450d08f98fe79' 
  AND token = '+Bxv43FbB+hxfbFSOzBuFTTjiL5xV4/8mwfHug+pD+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}