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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6396ae4127eff952eb4dc5fcf288e1d8ec63ab2a96420f9b75f7497a91f5208f' 
  AND token = 't6HCxPBKbnVJO2jh+mZ3f9lW1eRIyxiFoqK61IB9Bck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}